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Chronic inflammation can be behind everything from joint pain to fatigue

Lee BP-L, Imhof BA

The exact mechanism by which iNOS influences fibrosis is not fully understood, but the induction of hypoxia-inducible factor 1 (HIF-1),MMP-9 and the promotion of DNA damage by iNOS are being considered ( Moreover, CBD has been shown to influence activated HSCs by promoting their apoptosis and thus regression of fibrosis